materiaux

The concept is based on the interaction of resonant semiconductor iron oxide Fe2O3 nanoparticles with light. Particles previously loaded with the antitumor drug are injected in vivo and further accumulate at the tumor areas. In order to release the drug non-invasively, the carrier particles have to be light-sensitive. For this purpose, the polymer containers (capsules) can be modified with iron oxide resonant semiconductor nanoparticles. When irradiated with light, they get heated and induce drug release.

Researchers from Virginia Tech’s Future Materials Laboratory and MInDS Laboratory have recently demonstrated that high-intensity focused ultrasound (HIFU) is a promising, non-invasive stimulus with multiple superior and unique capabilities to induce localized heating and achieve temporal and spatial thermal effects in polymers.